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VOLUME 1 , ISSUE 2 ( May-August, 2022 ) > List of Articles

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Conservative Oxygen Therapy is the Way Forward in Critical Illness

Syed Nabeel Muzaffar, Shaik Arif Pasha, Neeraj Guttikonda

Keywords : Conservative oxygen therapy, Critical illness, Oxygen therapy

Citation Information : Muzaffar SN, Pasha SA, Guttikonda N. Conservative Oxygen Therapy is the Way Forward in Critical Illness. 2022; 1 (2):71-73.

DOI: 10.5005/jp-journals-10089-0030

License: CC BY-NC 4.0

Published Online: 31-12-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

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  1. Zhu H, Traore K, Santo A, et al. Oxygen and oxygen toxicity: the birth of concepts. React Oxyg Species (Apex) 2016;1(1):1–8. DOI: 10.20455/ros.2016.801
  2. de Jonge E, Peelen L, Keijzers PJ, et al. Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients. Crit Care 2008;12(6):R156. DOI: 10.1186/cc7150
  3. Singer M, Young PJ, Laffey JG, et al. Dangers of hyperoxia. Crit Care 2021;25(1):440. DOI: 10.13039/501100001659
  4. Holmberg MJ, Nicholson T, Nolan JP, et al. Oxygenation and ventilation targets after cardiac arrest: a systematic review and meta-analysis. Resuscitation 2020;152:107–115. DOI: 10.1016/j.resuscitation.2020.04.031
  5. Hofmann R, James SK, Jernberg T, et al. Oxygen therapy in suspected acute myocardial infarction. N Engl J Med 2017;377(13):1240–1249. DOI: 10.1056/NEJMoa1706222
  6. Meyhoff CS, Wetterslev J, Jorgensen LN, et al. Effect of high perioperative oxygen fraction on surgical site infection and pulmonary complications after abdominal surgery: the PROXI randomized clinical trial. JAMA 2009;302(14):1543–1550. DOI: 10.1001/jama.2009.1452
  7. Girardis M, Busani S, Damiani E, et al. Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial. JAMA 2016;316(15):1583–1589. DOI: 10.1001/jama.2016.11993
  8. Asfar P, Schortgen F, Boisramé-Helms J, et al. Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial. Lancet Respir Med 2017;5(3):180–190. DOI: 10.1016/S2213-2600(17)30046-2
  9. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. Lancet 2018;391(10131):1693–1705. DOI: 10.1016/s0140-6736(18)30479-3
  10. Young P, Mackle D, Bellomo R, et al. Conservative oxygen therapy for mechanically ventilated adults with sepsis: a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy (ICU-ROX). Intensive Care Med 2020;46(1):17–26. DOI: 10.1007/s00134-019-05857-x
  11. Barrot L, Asfar P, Mauny F, et al. Liberal or conservative oxygen therapy for acute respiratory distress syndrome. N Engl J Med 2020;382(11):999–1008. DOI: 10.1056/NEJMoa1916431
  12. Schjørring OL, Klitgaard TL, Perner A, et al. Lower or higher oxygenation targets for acute hypoxemic respiratory failure. N Engl J Med 2021;384(14):1301–1311. DOI: 10.1056/NEJMoa2032510
  13. Gelissen H, de Grooth HJ, Smulders Y, et al. Effect of low-normal vs high-normal oxygenation targets on organ dysfunction in critically ill patients: a randomized clinical trial. JAMA 2021;326(10):940–948. DOI: 10.1001/jama.2021.13011
  14. Martin DS, Grocott MP. Oxygen therapy in critical illness: precise control of arterial oxygenation and permissive hypoxemia. Crit Care Med 2013;41(2):423–432. DOI: 10.1097/CCM.0b013e31826a44f6
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