Journal of Acute Care

Register      Login

VOLUME 2 , ISSUE 1 ( January-April, 2023 ) > List of Articles

MEDICAL EDUCATION/CME

Double Plasma Molecular Adsorption System: A Modality of Treating Fulminant Hepatic Failure

HM Surya, Amrita Shah, Pradeep Rangappa, Ipe Jacob, Karthik Rao

Keywords : Artificial liver support system, BS330, Double plasma molecular adsorption system, Fulminant hepatic failure, HA330

Citation Information : Surya H, Shah A, Rangappa P, Jacob I, Rao K. Double Plasma Molecular Adsorption System: A Modality of Treating Fulminant Hepatic Failure. 2023; 2 (1):42-43.

DOI: 10.5005/jp-journals-10089-0064

License: CC BY-NC 4.0

Published Online: 23-08-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Fulminant hepatic failure (FHF) secondary to hepatitis A is a relatively rare but sometimes fatal condition. Treatment is largely supportive, with definitive treatment involving a liver transplant. Among the newer modalities developed to support the patient is the double plasma molecular adsorption system (DPMAS), which works on the principle of hemoadsorption. The system consists of two hemadsorption cartridges containing porous resin beads which adsorb toxins such as bilirubin and ammonia. We report such a case of FHF secondary to hepatitis A, which was treated with DPMAS.


HTML PDF Share
  1. Yao J, Li S, Zhou L, et al. Therapeutic effect of double plasma molecular adsorption system and sequential half-dose plasma exchange in patients with HBV-related acute-on-chronic liver failure. J Clin Apher 2019;34(4):392–398. DOI: 10.1002/jca.21690
  2. Ankawi G, Fan W, Pomarè Montin D, et al. A new series of sorbent devices for multiple clinical purposes: current evidence and future directions. Blood Purif 2019;47(1-3):94–100. DOI: 10.1159/000493523
  3. Bai W, Yao C, Mao D, et al. The clinical efficacy of double plasma molecular absorption system combined with plasma exchange in the treatment of acute-on-chronic liver failure: a systematic review and meta-analysis. J Healthc Eng 2022;2022:3139929. DOI: 10.1155/2022/3139929
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.