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VOLUME 1 , ISSUE 2 ( May-August, 2022 ) > List of Articles


Spontaneous Tumor Lysis Syndrome in an Undiagnosed Solid Organ Malignancy: Adenocarcinoma of the Colon

Sanjana Anand, R Rajavardhan, KR Anoop

Keywords : Adenocarcinoma colon, Critical care, Oncological emergency, Solid organ malignancy, Spontaneous tumor lysis syndrome, STLS, TLS, TLS in solid organ malignancy, Tumor lysis syndrome

Citation Information : Anand S, Rajavardhan R, Anoop K. Spontaneous Tumor Lysis Syndrome in an Undiagnosed Solid Organ Malignancy: Adenocarcinoma of the Colon. 2022; 1 (2):86-88.

DOI: 10.5005/jp-journals-10089-0029

License: CC BY-NC 4.0

Published Online: 31-12-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Spontaneous tumor lysis syndrome (TLS) is a rare life-threatening condition resulting from the lysis of a large number of tumor cells. It is more commonly seen in hematological malignancies than in solid tumors. We would like to bring to light the unique case of a 77-year-old gentleman with spontaneous TLS and undiagnosed adenocarcinoma of the colon. He initially presented with spontaneous TLS and was later diagnosed to have metastatic adenocarcinoma of the colon. Given its scarce occurrence and vague clinical presentation, there are very high chances of missing the diagnosis. Early recognition and prompt intervention would significantly reduce morbidity and mortality.

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