Spontaneous esophageal rupture due to an abrupt rise in intraluminal pressure combined with negative intrathoracic pressure (e.g., vomiting) is also known as Boerhaave's syndrome. This case study presents an overview of the syndrome, including morbidity, mortality, and treatment. A 45-year-old patient reported to the emergency department with retrosternal pain after forceful vomiting, which occurred 2 days earlier. Computed tomography (CT) showed a left-sided esophageal rupture along with pneumomediastinum and subcutaneous emphysema. Emergency thoracolaparotomy has been done, and esophageal perforation has been sealed. However, the patient's clinical condition deteriorated on the 5th postoperative day and he finally succumbed to sepsis and multiorgan failure.
De Schipper JP, Pull ter Gunne AF, Oostvogel HJ, et al. Spontaneous rupture of the oesophagus: Boerhaave's syndrome in 2008. Literature review and treatment algorithm. Dig Surg 2009;26(1):1–6. DOI: 10.1159/000191283
Pate JW, Walker WA, Cole FH Jr, et al. Spontaneous rupture of the esophagus: a 30-year experience. Ann Thorac Surg 1989;47(5):689–692. DOI: 10.1016/0003-4975(89)90119-7
Curci JJ, Horman MJ. Boerhaave's syndrome: the importance of early diagnosis and treatment. Ann Surg 1976;183(4):401–408. DOI: 10.1097/00000658-197604000-00013
Brauer RB, Liebermann-Meffert D, Stein HJ, et al. Boerhaave's syndrome: analysis of the literature and report of 18 new cases. Dis Esophagus 1997;10(1):64–68. DOI: 10.1093/dote/10.1.64
Jagminas L, Silverman RA. Boerhaave's syndrome presenting with abdominal pain and right hydropneumothorax. Am J Emerg Med 1996;14(1):53–56. DOI: 10.1016/S0735-6757(96)90016-9
Ring D, Vaccaro AR, Scuderi G, et al. Vertebral osteomyelitis after blunt traumatic esophageal rupture. Spine (Phila Pa 1976) 1995;20(1):98–101. DOI: 10.1097/00007632-199501000-00017
WB Marshall. Boerhaave syndrome: a case report. AANA J 2002;70(4):289–292. PMID: 12242927.
Janjua KJ. Boerhaave's syndrome. Postgrad Med J 1997;73(859):265–270. DOI: 10.1136/pgmj.73.859.265
Priviteri CA, Gay BB Jr. Spontaneous rupture of the esophagus, with report of five cases. Radiology 1951;57(1):48–57. DOI: 10.1148/57.1.48
Watts HD, Smith L. Complications of vomiting-Boerhaave and Mallory-Weiss syndromes. Western Journal of medicine 1974;121(1):50–54.
Van der Weg G, Wikkeling M, Van Leeuwen M, et al. A rare case of oesophageal rupture: Boerhaave's syndrome. Int J Emerg Med 2014;7:27. DOI: 10.1186/s12245-014-0027-2
Ivey TD, Simonowitz DA, Dillard DH, et al. Boerhaave syndrome. Successful conservative management in three patients with late presentation. Am J Surg 1981;141(5):531–533. DOI: 10.1016/0002-9610(81)90040-4
Carrott PW Jr, Low DE. Advances in the management of esophageal perforation. Thorac Surg Clin 2011;21(4):541–555. DOI: 10.1016/j.thorsurg.2011.08.002
Platel JP, Thomas P, Giudicelli R, et al. Esophageal perforations and ruptures: a plea for conservative treatment. Ann Chir 1997;51(6): 611–616.
Freeman RK, van Woerkom JM, Vyverberg A, et al. Esophageal stent placement for the treatment of spontaneous esophageal perforations. Ann Thorac Surg 2009;88(1):194–198. DOI: 10.1016/j.athoracsur.2009.04.004
Salo J, Sihvo E, Kauppi J, et al. Boerhaave's syndrome: lessons learned from 83 cases over three decades. Scand J Surg 2013;102(4):271–273. DOI: 10.1177/1457496913495338
Sabanathan S, Eng J, Richardson J. Surgical management of intrathoracic oesophageal rupture. Br J Surg 1994;81(6):863–865. DOI: 10.1002/bjs.1800810623
Lujan HJ, Lin PH, Boghossian SP, et al. Recurrent spontaneous rupture of the esophagus: an unusual late complication of Boerhaave's syndrome. Surgery 1997;122(3):634–636. DOI: 10.1016/s0039-6060(97)90139-2
