Fluid therapy is one of the interventions in a day-to-day practice. It is predominantly used for resuscitating a patient with acute circulatory failure. Fluid therapy aims to improve macrocirculation and thereby oxygen delivery at the tissue level. Various fluids are available for resuscitating patients, classified into crystalloids or colloids. Still, we lack the ideal fluid for resuscitation. Colloids once promised to be the ideal fluid for resuscitation, their effectiveness has been questioned by the recent evidence and also indicated the possible harm associated with its use. Is there any truth in the matter?
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